MP or BP: 161-162 °C(lit.) Appearance:white crystalline Application:A bronchodilator and coronary artery effect, and hae a diuretic effect.

Appearance White to almost white powder Identification Infrared absorption Solubility Practically insoluble in water, slightly soluble in methanol. It dissolves in dilute mineral acid. Appearance of solution Clear and colorless Specific optical rotation -30°~ -36° Water NMT 5.0% Sulphated ash NMT 0.1% Diethylamine NMT 0.5% Related substances Impurity D NMT 3.0% Impurity G NMT 1.0% Impurity J NMT 0.5% Impurity H NMT 0.5% Impurity B NMT 0.3% Impurity I NMT 0.2% Unspecified impurities NMT 0.1% Total of impurity NMT 5.5% Assay 94.0%~102.0%

Appearance Yellow crystalline powder Assay 99% min Loss on drying 5.0% max Residue on ignition 1.0% max

Appearance White crystalline powder, odorless Identification IR: Concordant with R.S HPLC: TR Concordant with R.S Specific rotation -49.0°~-55.0° Related substance 2.0% max Microbial limits Concordant with R.S Bacterial endotoxins Concordant with R.S Loss on drying 1.0% max Residue on ignition 0.2%max metals 20ppm max Assay(HPLC) 97.0-102.0

Description Crystalline powder,odorless Conforms Solubility Easily soluble in water, unsoluble in ethanol Conforms PH 6.0~7.5 6.9 Solution clarity and color solution should be clear and colorless Conforms Related substances 5’CMP 0.3% Simple impurity Total other impurity 0.01% 0.03% 0.10% Chloride 0.05% Conforms Ammonium 0.05% Conforms Fe 0.01% Conforms Phosphate 0.1% Conforms Loss on drying ≤6.0% 1.3% metals 0.002% Conforms Arsenide 0.0001% Conforms Bacterial Endotoxins 0.3EU/mg Conforms Microbial Limit Conforms Conforms Assay(on dried basis) ≥99.0% 99.8%

Appearance White powder Assay 99%min ash NMT0.1% Related substances NMT0.5% Loss on drying NMT 0.5% metals NMT 20 PPM

Appearance Orange red powder Identification IR Melting point 198~203℃ Crystallinity Meets the requirements Water ≤4.0% Residue on ignition ≤0.1% metals ≤0.001% Limit of solvent residues Acetone Total of acetone and alcohol Total impurities ≤0.5% ≤2.5% ≤2.0% Assay (HPLC) 98.0%-102.0% PH 4.5- 5.5 Solubility Soluble in water, in isotonic sodium chloride solution and in methanol. practically insoluble in chloroform, in ether and in other organic solvents

Appearance White or almost white crystalline power Identification Positive Loss on drying NMT 0.5% Melting range 223~229℃ Other steroids 0.80% Maximum impurities ≦1.0% Assay 97.0%~103.0%

Appearance White crystalline powder Solubility Freely soluble in methanol, ethanol, ethylacetate and chloroform, slightly soluble in water and 0.1M hydrochloric acid solution Identification IR,HPLC Water 0.3% max Residue on ignition 0.1% max metals 0.001% max Related substances Related compound B: 0.2% max Related compound C: 0.2% max Related compound D: 0.1% max Related compound E: 0.1% max Individual unspecified impurity: 0.1% max Total unspecified impurity: 0.2% max Total impurities: 0.5% max Residual solvents Dichloromethane: 0.06% max Chloroform: 0.006% max Ethanol: 0.5% max Cyclohexane: 0.08% Ethylacetate: 0.5% max Assay(on dry basis) 98.0%~102.0%

"Appearance White or off white crystalline powder Solubility Freely soluble in pyridine and acetic acid(100), sparingly soluble in methanol, slightly soluble in ethanol, very slightly soluble in water, and practically insoluble in diethyl ether Melting point 159~163℃ Identification (a) positive reaction must comply (b) positive reaction must comply (c) UV There is the strongest absorption at the waelength of 234~238nm and 275~278nm (d) IR There is absorption at 1741,1703,1585,1241 and 706 cm-1 Relative substances E-isomer 0.5% max Total impurities 1.0% max metals 10ppm max Loss on drying 1.0% max Toluene 0.089% max Ethanol 0.5% max Acetone 0.5% max Tetrahydrofuran 0.072% max Chlorobenzene 0.036% max Benzene 0.0002% max Residue on ignition 0.1% max Assay 98.5% min "

Appearance White or almost white powder Identification (1),(2),(3) must complies with the EP 7.0 Melting point 200℃~ 204℃ Specific optical rotation +58.0°~ +62.0° Impurity A Not more than 1.0% Impurity C Not more than 0.1% Any other impurity B,D,E,F,G,H,I Not more than 0.1% The unknown impurity Not more than 0.1% Total impurity Not more than 1.5% Sulfate Not more than 0.05% Chloride Not more than 0.02% Sulfated ash Not more than 0.1% Loss on drying Not more than 1.0% metals Not more than 10ppm Purity(HPLC) Not less than 99.0% Assay ( on dried basis) 99.0% ～ 101.0%

Appearance Light yellow powder or crystalline powder Solubility Soluble in water, slightly soluble in Methanol, Ethanol. Hardly soluble in Chloroform. Soluble in 0.1mol/L HCl solution Rotation +90.0°~ +100.0° IR absorption Max at 223,267,312,328,381nm and Min at 250,287,318,338nm Chloridate Meet requirement PH 3.0~5.0 Color of the liquid Complies requirement Related substance A: Single impurity ≤0.5% B: All impurity ≤1.0% Water 12% max Dichloromethane ＜0.06% Ash ＜0.2% metals ＜20ppm Heat source Complies requirement Assay(HPLC) ＞98%